Custom Peptides
Cayman Chemical TaccalonlIde B 10mg
A taccalonolide with anticancer activity; induces microtubule bundling, formation of abnormal mitotic spindles, and cell cycle arrest at the G2/M phase in HeLa cells at 0.8 µM; decreases the proliferation of HeLa cells (IC50 = 190 nM)
Cayman Chemical JWH 018 8quInolnyl caram 10mg
A structural analog of JWH 018 in which the naphthalenyl-methanone portion has been replaced by 8-quinolinyl carboxamide; intended for research and forensic applications
Cayman Chemical ADBPINCA pentnoIc ACD met 10mg
An expected compound produced by phase I metabolism of ADB-PINACA in vivo, based on the metabolism of comparable alkylindole CBs
Cayman Chemical TryptnthrIn 10mg
An alkaloid originally found to have antimicrobial actions; both 5-LO and COX-2 (IC50s = 600 and 64 nM, respectively); suppresses angiogenesis, blocking signaling through VEGFR2 at the level of ERK1/2 signaling; prevents ERK signaling through Nrf2, reducing oxidative stress-induced hepatocytotoxicity
Cayman Chemical 5-trns Latnoprost 10mg
A derivative of latanoprost (free acid), an isomer of latanoprost, and an analytical standard; may have similar biological activities as F-type prostaglandin cis isomers; a potential impurity in commercial preparations of latanoprost; intended as an analytical standard
Cayman Chemical 6-APBhydrochlorIde 10mg
An analytical reference standard categorized as a benzofuran; a metabolite of 6-MAPB; a potential metabolite 6-EAPB; has been found in seized samples suspected of containing NPS; intended for research and forensic applications
Cayman Chemical 1 3 7TrImethylurIc AcIdd9 10mg
An internal standard for the quantification of 1,3,7-trimethyluric acid by GC- or LC-MS
Cayman Chemical 4chloro2 5DMAhydrochlorI 10mg
An analytical reference standard categorized as an amphetamine; has a high addictive liability in rodents; has been associated with fatality; has been detected in blotter papers seized by law enforcement; intended for research and forensic applications
Cayman Chemical TASP0277308 10mg
An S1P1 antagonist (IC50 = 4.2 nM); selective for S1P1 over S1P3, S1P4, and S1P5 (IC50s = >10,000, >10,000, and 8,756 nM, respectively); inhibits S1P-induced [35S]GTPγS binding and forskolin-induced cAMP production in HEK293 cells expressing human S1P1 (IC50s = 7.8 and 4.3 nM, respectively); inhibits S1P-induced migration of CHO cells expressing human S1P1 (IC50 = 18 nM); induces lymphopenia in mice at 100 mg/kg; reduces bone erosion in a mouse model of collagen-induced arthritis; intrathecal administration reduces flinching and guarding behaviors in a mouse model of cancer-induced bone pain at 3 or 10 nmol/animal
Cayman Chemical RPalmItoyl 1methyl Ethno 10mg
A synthetic analog of PEA which incorporates an (R)-methyl group vicinal to the alcohol on the ethanolamine moiety, which may protect the molecule from enzymatic hydrolysis, leading to prolonged duration of action and enhanced potency in vivo; expected to show enhancement of the inhibitory activity of PEA on mast cells and other cells known to express the CB2 receptor
Cayman Chemical 2Omethyl PAF C18hydrAT 10mg
A synthetic PAF analog which contains an ether-linked methyl group at the sn-2 position; decreases plasma membrane fluidity, inhibits tumor cell invasiveness, and causes the release of large quantities of NO by a pathway involving activation of NOS
Cayman Chemical 5methoxyaEthyltryptamIn 10mg
An analog of α-ethyltryptamine which has recently been abused recreationally
Cayman Chemical MCOPPBhydroCLOrID hydrate 10mg
A potent, selective agonist for the nociceptin receptor (pKi = 10.1, EC50 = 0.39 nM); produces potent anxiolytic effects in rodents at 10 mg/kg, p.o. without inhibiting memory or motor function or inducing sedative side effects